Natural Killer Cells Antigen CD94 (KLRD1) Antibody
637€ (100 µl)
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Name
Natural Killer Cells Antigen CD94 (KLRD1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx113371
Tested Applications
ELISA, WB
Description
Killer Cell Lectin-Like Receptor Subfamily D, Member 1 Antibody is a Rabbit Polyclonal antibody against Killer Cell Lectin-Like Receptor Subfamily D, Member 1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Natural Killer Cells Antigen CD94 (KLRD1) Immunogen: Human KLRD1. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13241 |
| Gene ID | 3824 |
| NCBI Accession | NP_001107868.1, NM_001114396.1, NP_002253.1, NM_002262.3, NP_031360.1, NM_007334.2 |
| OMIM | 602894 |
| Alias | Natural killer cells antigen CD94,CD94,KP43,Killer cell lectin-like receptor subfamily D member 1,NK cell receptor |
| Background | Antibody anti-KLRD1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Killer Cell Lectin-Like Receptor D1 (KLRD1), commonly known as CD94, is a transmembrane protein that plays a crucial role in the immune system. Expressed on the surface of natural killer (NK) cells and certain subsets of T-cells, KLRD1 is primarily involved in recognizing and responding to infected or transformed cells. KLRD1 is part of the C-type lectin-like family of receptors, and its main function is to pair with other receptors (e.g., NKG2 family members) to mediate immune surveillance by recognizing peptide-loaded MHC class I molecules. Unlike other immune receptors that directly recognize pathogenic antigens, KLRD1 primarily regulates immune response through interaction with HLA-E, a non-classical MHC class I molecule presenting peptide sequences derived from other MHC class I molecules.
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