Natural Killer Cells Antigen CD94 (KLRD1) Antibody
364€ (100 µg)
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Name
Natural Killer Cells Antigen CD94 (KLRD1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx413968
Tested Applications
FCM
Description
Natural Killer Cells Antigen CD94 (KLRD1) Antibody is a Rat Monoclonal antibody against Natural Killer Cells Antigen CD94 (KLRD1).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Natural Killer Cells Antigen CD94 (KLRD1) |
| Host | Rat |
| Reactivity | Mouse |
| Assay Type | Concentration: 1.0 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Purification | Purified |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O54707 |
| Alias | Natural killer cells antigen CD94,CD94,KP43,Killer cell lectin-like receptor subfamily D member 1,NK cell receptor |
| Background | Antibody anti-KLRD1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Killer Cell Lectin-Like Receptor D1 (KLRD1), commonly known as CD94, is a transmembrane protein that plays a crucial role in the immune system. Expressed on the surface of natural killer (NK) cells and certain subsets of T-cells, KLRD1 is primarily involved in recognizing and responding to infected or transformed cells. KLRD1 is part of the C-type lectin-like family of receptors, and its main function is to pair with other receptors (e.g., NKG2 family members) to mediate immune surveillance by recognizing peptide-loaded MHC class I molecules. Unlike other immune receptors that directly recognize pathogenic antigens, KLRD1 primarily regulates immune response through interaction with HLA-E, a non-classical MHC class I molecule presenting peptide sequences derived from other MHC class I molecules.
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