NAD-Dependent Protein Deacetylase Sirtuin-1 (SIRT1) Antibody
260€ (50 µg)
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935106861
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name
NAD-Dependent Protein Deacetylase Sirtuin-1 (SIRT1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx456809
tested applications
ELISA, WB, IHC
Description
NAD-Dependent Protein Deacetylase Sirtuin-1 (SIRT1) Antibody is a Rabbit polyclonal antibody for the detection of Human, Rat NAD-Dependent Protein Deacetylase Sirtuin-1 (SIRT1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: NAD-Dependent Protein Deacetylase Sirtuin-1 (SIRT1) Immunogen: Recombinant NAD-Dependent Protein Deacetylase Sirtuin-1 (Ile194-Ser747) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96EB6 |
| Gene ID | 23411 |
| NCBI Accession | NP_001135970.1 |
| Alias | SIR2,SIR2L1,SIR2alpha,SIR2-like protein 1,Hsir2,NAD-dependent protein deacylase sirtuin-1 |
| Background | Antibody anti-SIRT1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
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