Myosin Binding Protein C, Slow Type (MYBPC1) Antibody
377€ (100 µg)
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Name
Myosin Binding Protein C, Slow Type (MYBPC1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx235454
Tested Applications
ELISA, WB, IHC
Description
MYBPC1 Antibody is a Rabbit Polyclonal against MYBPC1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Myosin Binding Protein C, Slow Type (MYBPC1) Immunogen: myosin binding protein C, slow type |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 135-140 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q00872 |
| Gene ID | 4604 |
| OMIM | 160794 |
| Alias | LCCS4,CMYP16,MYBPCC,MYBPCS,MYOTREM,ssMyBP-C,Slow MyBP-C,C-protein skeletal muscle slow isoform |
| Background | Antibody anti-MYBPC1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
MYBPC1 is a structural protein predominantly expressed in slow-twitch skeletal muscles, where it plays a critical role in maintaining the structural integrity of sarcomeres and regulating muscle contraction. By interacting with myosin and actin filaments, it modulates their binding interactions and stabilizes the thick filaments within the muscle fibers. This ensures the proper alignment and function of the contractile apparatus. Mutations in MYBPC1 have been associated with various myopathies, including those characterized by muscle weakness and reduced contractility, particularly in conditions affecting slow-twitch muscles. These mutations can lead to disruptions in sarcomere assembly and force transmission. MYBPC1’s role in muscle biomechanics makes it an important focus of research into muscle function and disease mechanisms.
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