Myosin-Binding Protein C, Fast-Type (MYBPC2) Antibody

169€ (20 µl)
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935106861
info@markelab.com
name
Myosin-Binding Protein C, Fast-Type (MYBPC2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx320808
tested applications
ELISA, IHC
Description
MYBPC2 Antibody is a Rabbit Polyclonal against MYBPC2.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Myosin-Binding Protein C, Fast-Type (MYBPC2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 20 µl |
Size 2 | 50 µl |
Size 3 | 100 µl |
Size 4 | 200 µl |
Size 5 | 1 ml |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q14324 |
Gene ID | 4606 |
OMIM | 160793 |
Alias | MYBPC; MYBPCF; fsMyBP-C,C-protein skeletal muscle fast isoform,Fast MyBP-C |
Background | Antibody anti-MYBPC2 |
Status | RUO |
Descripción
MYBPC2 is primarily localized in fast-twitch skeletal muscles, where it plays a pivotal role in regulating sarcomere assembly and ensuring efficient muscle contraction during rapid and high-force activities. This protein associates with the thick filaments and modulates the interactions between myosin and actin filaments, contributing to the functional stability of the sarcomere under dynamic conditions. Dysregulation or mutations in MYBPC2 may compromise muscle performance, particularly in activities requiring bursts of strength or speed, and can lead to structural instability within muscle fibers. MYBPC2 continues to be investigated for its potential involvement in muscle diseases and as a marker of muscle adaptation or dysfunction.
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