Myosin Binding Protein C, Cardiac (MYBPC3) Antibody (HRP)
169€ (20 µg)
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Name
Myosin Binding Protein C, Cardiac (MYBPC3) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx109012
Tested Applications
ELISA
Description
Myosin-binding protein C, cardiac-type Antibody (HRP) is a Rabbit Polyclonal antibody against Myosin-binding protein C, cardiac-type conjugated to HRP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Myosin Binding Protein C, Cardiac (MYBPC3) Immunogen: Recombinant rat Myosin-binding protein C, cardiac-type (645-864AA). |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P56741 |
| Gene ID | 295929 |
| Alias | FHC,CMH4,CMD1MM,LVNC10,MYBP-C,cMyBP-C,C-protein cardiac muscle isoform,Cardiac MyBP-C,Myosin-binding protein C, cardiac-type |
| Background | Antibody anti-MYBPC3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
MYBPC3 is a crucial component of the sarcomere in cardiac muscles, where it regulates cardiac contractility and stabilizes the structural framework of the thick filament. Through its interactions with myosin and actin, it modulates the force and efficiency of cardiac muscle contraction, playing a central role in maintaining the heart’s mechanical function. Mutations in MYBPC3 are a common genetic cause of hypertrophic cardiomyopathy (HCM), a condition characterized by the abnormal thickening of the heart muscle that can lead to heart failure and arrhythmias. These mutations often result in impaired sarcomere function and contribute to maladaptive cardiac remodeling. Research on MYBPC3 focuses on its role in cardiomyopathy pathogenesis and its potential as a therapeutic target for improving heart function in affected individuals.
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