Myocyte-Specific Enhancer Factor 2A (MEF2A) Antibody
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Description
MEF2A Antibody is a Mouse Monoclonal against MEF2A.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Myocyte-Specific Enhancer Factor 2A (MEF2A) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q02078 |
| Gene ID | 4205 |
| OMIM | 600660 |
| Background | Antibody anti-MEF2A |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Human MEF2A (Myocyte enhancer factor 2A) ELISA Kit
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MEF2A antibody
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
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