Mouse WD repeat and FYVE domain-containing protein 3 (WDFY3) ELISA Kit

Este producto es parte de WDFY - WD repeat and FYVE domain containing
Product Graph
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse WD repeat and FYVE domain-containing protein 3 (WDFY3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx553354
tested applications
ELISA

Description

Mouse WD repeat and FYVE domain-containing protein 3 (WDFY3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse WD repeat and FYVE domain-containing protein 3 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
WD repeat and FYVE domain-containing protein 3 (WDFY3)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6VNB8
Gene ID
72145
Alias
ALFY,BCHS,MCPH18,ZFYVE25,KIAA0993,Autophagy-linked FYVE protein (Alfy)
Background
Elisa kits for WDFY3
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

WD repeat and FYVE domain containing 3 (WDFY3) is a protein that contains WD repeats and a FYVE domain, both of which are known for their roles in protein interactions and intracellular signaling. The WD repeats are typically involved in mediating interactions with other proteins, often forming large complexes that regulate various cellular processes. The FYVE domain in WDFY3 allows it to bind to phosphoinositides, specifically to the lipid molecules found in the membrane of endosomes and other intracellular vesicles. This interaction is crucial for the protein's role in vesicular trafficking and membrane dynamics, where it is involved in sorting and regulating endocytic cargo. Additionally, WDFY3 has been implicated in cellular processes such as autophagy and immune responses, both of which are essential for maintaining cellular homeostasis and immunity. Dysregulation of WDFY3 has been associated with several disorders, particularly those affecting cellular transport and immune function. Understanding how WDFY3 functions within the endosomal network and its role in various signaling pathways is critical for the development of therapeutic strategies aimed at diseases involving vesicular trafficking and immune dysregulation.

Related Products

FNab09479

WDFY3 antibody

Required for selective autophagy(aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies(p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.

Ver Producto
abx239479

WD Repeat And FYVE Domain-Containing Protein 3 (WDFY3) Antibody

WDFY3 Antibody is a Rabbit Polyclonal against WDFY3.

Ver Producto
abx334243

WD repeat and FYVE domain-containing protein 3 (WDFY3) Antibody

WDFY3 Antibody is a Rabbit Polyclonal against WDFY3.

Ver Producto