Mouse Vinculin (VCL) Protein
975€ (50 µg)
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935106861
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name
Mouse Vinculin (VCL) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691916
tested applications
SDS-PAGE
Description
Vinculin (VCL) Protein is a recombinant Mouse protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Vinculin (VCL) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Gln1066 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | Calculated MW: 118.2 kDa Observed MW (SDS-PAGE): 118 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4, containing 5% Trehalose, 5% Mannitol and 0.01% Tween-80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q64727 |
| NCBI Accession | NP_033528.3 |
| Background | Protein VCL |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile H2O to make a stock solution of 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg (LAL method). Centrifuge before opening to ensure complete recovery of vial contents. |
Descripción
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Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
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