Mouse Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B) CLIA Kit

Este producto es parte de TNFRSF1B - TNF receptor superfamily member 1B
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Mouse Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196326
tested applications
CLIA

Description

Mouse Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
3.13 pg/ml - 200 pg/ml
Sensitivity
1.88 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Tumor necrosis factor receptor superfamily member 1B,p75,TBPII,TNFBR,TNFR2,CD120b,TNFR1B,TNFR80,TNF-R75,p75TNFR,TNF-R-II,Tumor necrosis factor receptor 2,p80 TNF-alpha receptor
Background
CLIA Kits TNFRSF1B
Status
RUO
Note
The validity for this kit is 6 months.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

TNFRSF1B, also known as Tumor Necrosis Factor Receptor Superfamily Member 1B or TNFR2, is a cell surface receptor predominantly expressed on immune cells, including regulatory T cells (Tregs), endothelial cells, and neurons. TNFR2 is one of the two primary receptors for tumor necrosis factor-alpha (TNF-α), along with TNFR1 (TNFRSF1A). Although TNFR1 and TNFR2 both bind TNF-α, they have unique and overlapping roles within immune responses. TNFR2 primarily activates pathways that promote cell survival, tissue regeneration, and anti-inflammatory responses, differentiating it from TNFR1, which is more commonly associated with apoptosis and pro-inflammatory signaling. The TNFRSF1B gene is located on chromosome 1p36.22 and encodes a receptor of 461 amino acids. TNFR2 is a key component in regulating inflammation, modulating T cell activity, and contributing to vascular health. Its interaction with TNF-α can activate both canonical (NF-κB) and non-canonical pathways, resulting in varying cellular responses depending on the cellular environment and receptor activation context.

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