Mouse Tumor Necrosis Factor Receptor Superfamily Member 12A / TWEAKR (TNFRSF12A) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits TNFRSF12A
proveedor
Abbexareference
abx520724Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Tumor Necrosis Factor Receptor Superfamily Member 12A / TWEAKR (TNFRSF12A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Tumor Necrosis Factor Receptor Superfamily Member 12A / TWEAKR (TNFRSF12A) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TNFRSF12A, also known as FN14 (Fibroblast Growth Factor Inducible 14), is a member of the tumor necrosis factor receptor superfamily (TNFRSF). This receptor is highly responsive to cellular stress signals, tissue damage, and inflammation, and it plays an essential role in tissue remodeling, inflammation, and wound healing. FN14 is particularly notable for its role as the primary receptor for TWEAK (TNF-like weak inducer of apoptosis), a member of the TNF superfamily of ligands. The binding of TWEAK to TNFRSF12A activates various downstream signaling pathways that influence processes including cell survival, proliferation, migration, and apoptosis. Its expression is typically low in most normal tissues but is upregulated under stress conditions such as injury, inflammation, or exposure to growth factors. Elevated levels of TNFRSF12A have been observed in a variety of pathological conditions, particularly in inflammatory diseases, cancer, cardiovascular disease, and fibrosis, where its activity is often associated with promoting cell survival, angiogenesis, and tissue remodeling.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Receptor Superfamily Member 12A / TWEAKR (TNFRSF12A)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Tumor necrosis factor receptor superfamily member 12A,FN14,CD266,TWEAKR,Fibroblast growth factor-inducible immediate-early response protein 14 (FGF-inducible 14)
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
TNFRSF12A
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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