Mouse Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) ELISA Kit

Este producto es parte de TNFSF10 - TNF superfamily member 10
Mouse Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

643.5€ (96 tests)

Elisa kits for TNFSF10

proveedor

Abbexa

reference

abx585043

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


Background

TNFSF10, also known as TRAIL (TNF-related apoptosis-inducing ligand), is a cytokine in the tumor necrosis factor (TNF) superfamily, known for its ability to induce apoptosis selectively in cancerous or infected cells. TRAIL is a type II transmembrane protein expressed by various immune cells, such as T cells, NK cells, and macrophages, and plays a pivotal role in immune surveillance and regulation. Unlike other TNF family ligands, TRAIL exhibits the unique ability to preferentially trigger cell death in transformed cells, sparing most normal cells. Its selective cytotoxicity has made it a significant target for cancer therapeutics and an area of research for treatments against viral infections and immune regulation. TRAIL’s role in apoptosis is critical in regulating immune cell function, homeostasis, and tolerance, as it can trigger cell death through both extrinsic and intrinsic pathways. Due to this, TRAIL is an essential component of the immune response to abnormal or damaged cells and has garnered attention as a therapeutic target due to its ability to promote cell death in cancerous or infected cells with minimal toxicity to healthy tissues.

Características del producto

category

ELISA Kits


immunogen target

Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.06 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

Tumor necrosis factor ligand superfamily member 10,TL2,APO2L,CD253,TANCR,TRAIL,Apo-2L,TNLG6A,Apo-2 ligand,Apo-2L,TNF-related apoptosis-inducing ligand


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TNFSF10


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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reference

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reactivity

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