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Mouse Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
525€ (96 tests)
Elisa Kits TNFSF10
proveedor
Abbexareference
abx254483Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
TNFSF10, also known as TRAIL (TNF-related apoptosis-inducing ligand), is a cytokine in the tumor necrosis factor (TNF) superfamily, known for its ability to induce apoptosis selectively in cancerous or infected cells. TRAIL is a type II transmembrane protein expressed by various immune cells, such as T cells, NK cells, and macrophages, and plays a pivotal role in immune surveillance and regulation. Unlike other TNF family ligands, TRAIL exhibits the unique ability to preferentially trigger cell death in transformed cells, sparing most normal cells. Its selective cytotoxicity has made it a significant target for cancer therapeutics and an area of research for treatments against viral infections and immune regulation. TRAIL’s role in apoptosis is critical in regulating immune cell function, homeostasis, and tolerance, as it can trigger cell death through both extrinsic and intrinsic pathways. Due to this, TRAIL is an essential component of the immune response to abnormal or damaged cells and has garnered attention as a therapeutic target due to its ability to promote cell death in cancerous or infected cells with minimal toxicity to healthy tissues.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10)
reactivity
Mouse
test range
15.6 pg/ml - 1000 pg/ml
sensitivity
9.38 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Tumor necrosis factor ligand superfamily member 10,TL2,APO2L,CD253,TANCR,TRAIL,Apo-2L,TNLG6A,Apo-2 ligand,Apo-2L,TNF-related apoptosis-inducing ligand
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
TNFSF10
dry ice
No
uniprot id
NCBI accession
NP_033451.1
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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