Mouse Transmembrane Emp24 Domain-Containing Protein 9 (TMED9) ELISA Kit
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Description
Mouse Transmembrane emp24 domain-containing protein 9 ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transmembrane emp24 domain-containing protein 9 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Transmembrane Emp24 Domain-Containing Protein 9 (TMED9) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | GMP25, HSGP25L2G, p24a2, p24alpha2, p25,GP25L2 |
| Background | Elisa kits for TMED9 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TMED9 is a critical member of the p24 protein family that regulates protein trafficking between the endoplasmic reticulum (ER), ER-Golgi intermediate compartment (ERGIC), and the Golgi apparatus. It functions as a cargo receptor, facilitating the export of correctly folded proteins through COPII-coated vesicles and supporting retrograde retrieval via COPI transport machinery. TMED9 also regulates protein quality control, ensuring proper sorting, maturation, and recycling of secretory and membrane-bound proteins. It plays additional roles in signaling pathways, including Wnt and growth factor signaling, by modulating receptor trafficking and localization at the plasma membrane. TMED9 is widely expressed, particularly in secretory cells, immune tissues, and proliferative compartments. Dysregulation of TMED9 has been associated with cancers and metabolic diseases, where altered trafficking dynamics impair protein secretion and receptor signaling. Knockdown studies reveal defects in vesicle formation, impaired Golgi organization, and disrupted cellular homeostasis, emphasizing its essential role in coordinating vesicular transport, protein quality control, and signaling regulation.
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