Mouse TRAF3-interacting protein 1 (TRAF3IP1) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TRAF3IP1
proveedor
Abbexareference
abx533078Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse TRAF3-interacting protein 1 (TRAF3IP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse TRAF3-interacting protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TRAF3IP1, also known as IFT54, is a signaling adaptor protein that interacts with TRAF3 and participates in immune signaling and intracellular transport processes. It is a critical component of the intraflagellar transport (IFT) machinery, which regulates ciliogenesis and ciliary signaling pathways by mediating the transport of cargo proteins within primary cilia. TRAF3IP1 plays a key role in developmental processes, cell signaling, and tissue homeostasis by facilitating cilia assembly and function. It is expressed in ciliated epithelial tissues, immune cells, and the brain, where it regulates processes such as Hedgehog signaling, immune response, and cytoskeletal organization. Dysregulation or mutations in TRAF3IP1 are associated with ciliopathies, including Joubert syndrome and nephronophthisis, due to defective cilia function and signaling. Knockout studies reveal impaired ciliogenesis, disrupted signaling pathways, and developmental abnormalities, emphasizing its essential role in cilia-mediated signaling and cellular organization.
Características del producto
category
ELISA Kits
immunogen target
TRAF3-interacting protein 1 (TRAF3IP1)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
IFT54, MIPT3,Interleukin-13 receptor alpha 1-binding protein 1,Intraflagellar transport protein 54 homolog, CFAP116, FAP116, IFT54, MIP-T3, SLSN9
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TRAF3IP1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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