Mouse TNFRSF13C/BAFFR (B-Cell Activation Factor Receptor) ELISA Kit
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name
Mouse TNFRSF13C/BAFFR (B-Cell Activation Factor Receptor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0186
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 78.125-5000pg/ml |
| Sensitivity | 46.875pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q9D8D0 |
| Alias | Tumor necrosis factor receptor superfamily member 13C,BAFFR,CD268,CVID4,BAFF-R,BROMIX,prolixin,B-cell-activating factor receptor,BAFF receptor,BAFF-R |
| Background | Elisa kits for TNFRSF13C |
| Status | RUO |
TNFRSF13C, also known as the B-cell activating factor receptor (BAFF-R), is a critical receptor involved in the regulation of B cell survival and maturation within the immune system. It belongs to the tumor necrosis factor receptor superfamily (TNFRSF), with BAFF-R specifically binding BAFF (B-cell activating factor), also known as TNFSF13B. BAFF-R signaling is essential for the differentiation of B cells and their progression through developmental stages, playing a crucial role in both innate and adaptive immunity. Dysfunction in TNFRSF13C signaling has been implicated in immune-related disorders, including autoimmune diseases and immunodeficiencies. Genetic mutations or dysregulation in BAFF-R and BAFF signaling pathways are associated with conditions such as Systemic Lupus Erythematosus (SLE) and Common Variable Immunodeficiency (CVID), as they can lead to abnormal B cell activity, autoreactivity, and altered antibody production. This receptor is also studied as a therapeutic target for autoimmune diseases, with strategies aimed at modulating BAFF levels to control B cell activity.
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