Mouse Tumor Necrosis Factor (TNF) Protein
proveedor
Abbexareference
abx670284Tested Applications
ELISA, WBreactivity
status
RUOclonality
Descripción
Mouse Tumor Necrosis Factor (TNF) Protein is a Recombinant protein.
Background
Tumor necrosis factor (TNF), also known as tumor necrosis factor alpha (TNF-α), is a multifaceted protein with characteristics of both an adipokine and a cytokine. It belongs to the TNF superfamily, a group of transmembrane proteins characterized by a homologous TNF domain. TNFα is produced and secreted by a variety of cells, including activated monocytes, macrophages, B cells, T cells, and fibroblasts. In its role as an adipokine, TNF contributes to insulin resistance and is linked to the development of type 2 diabetes in cases of obesity. As a cytokine, TNF plays a crucial role in cell signaling within the immune system. Has particular significance in sepsis. In animal models, the use of anti-TNFα treatments has been shown to reduce mortality during sepsis. Furthermore, in septic patients, the levels of TNFα in the bloodstream have been found to correlate with mortality rates. TNF is also known by several aliases, including TNF, DIF, TNF-alpha, TNFA, TNFSF2, Tumour necrosis factor, TNF-α, TNLG1F, and Tumor necrosis factor alpha.
Características del producto
category
Proteins and Peptides
origin
Mouse
immunogen target
Tumor Necrosis Factor (TNF)
conjugation
Unconjugated
form
Lyophilized
tested applications
ELISA, WB
size 1
20 µg
buffer
Prior to lyophilization: 10 mM Sodium Phosphate
storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
or code
TNF
dry ice
Yes
availability
Shipped within 3-7 working days.
alias
TNF,DIF,TNF-alpha,TNFA,TNFSF2,Tumour necrosis factor,TNF-α,TNLG1F,Tumor necrosis factor alpha, Cachectin
uniprot id
note
This product is for research use only. This product is shipped with dry ice. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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