Mouse THO Complex Subunit 4 / THOC4 (ALYREF) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse THO Complex Subunit 4 / THOC4 (ALYREF) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx549610
tested applications
ELISA
Description
Mouse THO Complex Subunit 4 / THOC4 (ALYREF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse THO Complex Subunit 4 / ALY concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | THO Complex Subunit 4 / THOC4 (ALYREF) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.09 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O08583 |
| Gene ID | 21681 |
| Alias | ALYREF,ALY,BEF,THOC4 |
| Background | Elisa kits for ALYREF |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ALYREF, also known as Aly/REF export factor, is a protein involved in the process of mRNA export from the nucleus to the cytoplasm in eukaryotic cells. mRNA (messenger RNA) carries genetic information from the DNA in the cell nucleus to the cytoplasm, where it serves as a template for protein synthesis. ALYREF is a member of the Aly/REF family of proteins and is essential for the export of mature mRNA molecules from the nucleus. It functions by interacting with other proteins and RNA molecules to facilitate the assembly of messenger ribonucleoprotein (mRNP) complexes, which are then transported through nuclear pores to the cytoplasm.The role of ALYREF in mRNA export is particularly important for the regulation of gene expression and the proper functioning of cells. Dysregulation of mRNA export can lead to various cellular abnormalities and diseases, including cancer and developmental disorders. ALYREF interacts with other proteins involved in mRNA export, such as the TREX (TRanscription-EXport) complex, which helps recruit ALYREF to mRNA molecules and facilitates their export. Additionally, ALYREF interacts with specific RNA sequences and structures, such as the mRNA export element (REF) found in certain viral RNAs, to promote their export from the nucleus.
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