Mouse T-Cell Surface Glycoprotein CD5 (CD5) Protein
1118€ (100 µg)
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Name
Mouse T-Cell Surface Glycoprotein CD5 (CD5) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx691864
Tested Applications
SDS-PAGE
Description
Mouse CD5 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the extracellular domain of mouse CD5 (NP_031676.3) (Met 1-Pro 371) was expressed, with a C-terminal polyhistidine tag.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | CD5 |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Pro371 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | 39.4 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_031676.3 |
| Alias | T1,LEU1,T-cell surface glycoprotein CD5,Lymphocyte antigen T1/Leu-1 |
| Background | Protein CD5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
The CD5 molecule is a type I transmembrane glycoprotein primarily expressed on the surface of T cells and a subset of B cells known as B1a cells. CD5 functions as an immunomodulatory receptor, playing a critical role in T-cell activation, immune tolerance, and B-cell signaling. Its primary role is in regulating immune responses by controlling the threshold of antigen receptor signaling in both T and B cells. CD5 is also involved in maintaining the delicate balance between immune activation and immune tolerance, which prevents autoimmune responses while ensuring effective immunity. CD5 belongs to the scavenger receptor cysteine-rich (SRCR) superfamily of receptors, a group of molecules known to be involved in diverse biological functions, including immunity, apoptosis, and cellular adhesion. CD5 is especially notable for its role as a negative regulator of T-cell receptor (TCR) and B-cell receptor (BCR) signaling. This regulatory capacity makes CD5 crucial in maintaining immune homeostasis.
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