Mouse T-Cell Surface Glycoprotein CD5 (CD5) Protein
247€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse T-Cell Surface Glycoprotein CD5 (CD5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690066
tested applications
SDS-PAGE
Description
Mouse T-Cell Surface GlycoProtein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse T-Cell Surface Glycoprotein CD5 is produced by our Mammalian expression system and the target gene encoding Gln24-Asn370 is expressed with a 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | T-Cell Surface GlycoProtein |
| Host | Human |
| Origin | Mouse |
| Observed MW | Molecular Weight: 38.9 kDa Sequence Fragment: Met1-Pro371 Tag: C-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| NCBI Accession | NP_031676.3 |
| Alias | T1,LEU1,T-cell surface glycoprotein CD5,Lymphocyte antigen T1/Leu-1 |
| Background | Protein CD5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
The CD5 molecule is a type I transmembrane glycoprotein primarily expressed on the surface of T cells and a subset of B cells known as B1a cells. CD5 functions as an immunomodulatory receptor, playing a critical role in T-cell activation, immune tolerance, and B-cell signaling. Its primary role is in regulating immune responses by controlling the threshold of antigen receptor signaling in both T and B cells. CD5 is also involved in maintaining the delicate balance between immune activation and immune tolerance, which prevents autoimmune responses while ensuring effective immunity. CD5 belongs to the scavenger receptor cysteine-rich (SRCR) superfamily of receptors, a group of molecules known to be involved in diverse biological functions, including immunity, apoptosis, and cellular adhesion. CD5 is especially notable for its role as a negative regulator of T-cell receptor (TCR) and B-cell receptor (BCR) signaling. This regulatory capacity makes CD5 crucial in maintaining immune homeostasis.
