Mouse T-Cell Surface Glycoprotein CD3 Delta Chain (CD3D) ELISA Kit
611€ (96 tests)
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935106861
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name
Mouse T-Cell Surface Glycoprotein CD3 Delta Chain (CD3D) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx505776
tested applications
ELISA
Description
Mouse Cluster of differentiation 3 ELISA Kit is an ELISA Kit against Cluster of differentiation 3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | T-Cell Surface Glycoprotein CD3 Delta Chain (CD3D) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.391 ng/ml - 25 ng/ml |
| Sensitivity | 0.24 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | T3D,IMD19,CD3DELTA,CD3-DELTA,T-cell surface glycoprotein CD3 delta chain,T-cell receptor T3 delta chain |
| Background | Elisa kits for CD3D |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CD3D, the delta subunit of the T-cell receptor (TCR) complex, plays a critical role in T-cell development and activation, which are essential components of the adaptive immune system. The TCR complex is responsible for recognizing antigens presented by major histocompatibility complex (MHC) molecules on the surface of antigen-presenting cells (APCs), allowing T-cells to initiate immune responses against pathogens. The CD3D subunit, along with other CD3 subunits (CD3E, CD3G, and CD3Z), functions as part of the CD3 complex, which couples with the TCR α/β heterodimer to mediate signal transduction following antigen recognition. The CD3D gene, located on chromosome 11q23, encodes the CD3δ chain, a 20-25 kDa protein essential for the assembly and function of the TCR complex. The CD3 complex, including the CD3D subunit, is expressed in all T lymphocytes and plays a vital role in transmitting signals from the extracellular environment to the interior of the cell, initiating downstream signaling cascades essential for T-cell activation, differentiation, and survival.
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CD3D antibody
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
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