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Mouse Suppressor of cytokine signaling 7 (SOCS7) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits SOCS7
proveedor
Abbexareference
abx546668Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Suppressor of cytokine signaling 7 (SOCS7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Suppressor of cytokine signaling 7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
SOCS7 is a member of the SOCS family that negatively regulates cytokine signaling pathways, particularly those involving the JAK/STAT pathway, by targeting receptor complexes and downstream components for proteasomal degradation via its SOCS box. Unlike other SOCS proteins, SOCS7 has additional roles in regulating insulin signaling, cellular localization of signaling proteins, and DNA damage responses. SOCS7 interacts with the nuclear adaptor protein NCK and modulates actin cytoskeletal dynamics, cell polarity, and nuclear signaling. It is highly expressed in tissues such as the brain, pancreas, and immune cells, where it participates in processes like insulin homeostasis, cell migration, and cytokine regulation. Dysregulation of SOCS7 is associated with metabolic disorders, insulin resistance, and immune dysfunction. Knockout studies reveal defects in glucose homeostasis, increased susceptibility to DNA damage, and disrupted immune responses, highlighting its multifunctional role in cytokine signaling, metabolism, and cell signaling regulation.
Características del producto
category
ELISA Kits
immunogen target
Suppressor of cytokine signaling 7 (SOCS7)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
SOCS7, NAP4, NCKAP4, suppressor of cytokine signaling 7,nck
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SOCS7
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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