Mouse Suppressor of cytokine signaling 7 (SOCS7) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Suppressor of cytokine signaling 7 (SOCS7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx546668
tested applications
ELISA
Description
Mouse Suppressor of cytokine signaling 7 (SOCS7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Suppressor of cytokine signaling 7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Suppressor of cytokine signaling 7 (SOCS7) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8VHQ2 |
| Gene ID | 192157 |
| Alias | SOCS7, NAP4, NCKAP4, suppressor of cytokine signaling 7,nck |
| Background | Elisa kits for SOCS7 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
SOCS7 is a member of the SOCS family that negatively regulates cytokine signaling pathways, particularly those involving the JAK/STAT pathway, by targeting receptor complexes and downstream components for proteasomal degradation via its SOCS box. Unlike other SOCS proteins, SOCS7 has additional roles in regulating insulin signaling, cellular localization of signaling proteins, and DNA damage responses. SOCS7 interacts with the nuclear adaptor protein NCK and modulates actin cytoskeletal dynamics, cell polarity, and nuclear signaling. It is highly expressed in tissues such as the brain, pancreas, and immune cells, where it participates in processes like insulin homeostasis, cell migration, and cytokine regulation. Dysregulation of SOCS7 is associated with metabolic disorders, insulin resistance, and immune dysfunction. Knockout studies reveal defects in glucose homeostasis, increased susceptibility to DNA damage, and disrupted immune responses, highlighting its multifunctional role in cytokine signaling, metabolism, and cell signaling regulation.
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