Mouse Stress-Induced-Phosphoprotein 1 (STIP1) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for STIP1
proveedor
Abbexareference
abx556089Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Stress-Induced-Phosphoprotein 1 (STIP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Stress-induced-phosphoprotein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
STIP1 is a co-chaperone protein that coordinates the activities of heat shock proteins HSP70 and HSP90, facilitating protein folding, stability, and transport under stress conditions. It functions as a scaffold protein that regulates the transfer of client proteins between HSP70 and HSP90, ensuring proper protein maturation, stabilization, and degradation. STIP1 is ubiquitously expressed and is critical for processes such as protein quality control, cellular stress responses, and signal transduction. It also plays a role in cancer progression, where it stabilizes oncogenic signaling proteins and promotes tumor cell survival and proliferation. Dysregulation of STIP1 is associated with neurodegenerative diseases, such as Huntington's and Alzheimer's, where impaired chaperone function leads to protein aggregation and cellular dysfunction. Knockout studies reveal increased sensitivity to stress, defects in protein homeostasis, and impaired cell viability, emphasizing its role in protein folding, stress response, and maintaining cellular proteostasis.
Características del producto
category
ELISA Kits
immunogen target
Stress-Induced-Phosphoprotein 1 (STIP1)
reactivity
Mouse
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
< 15.2 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
STIP1,HEL-S-94n, HOP, IEF-SSP-3521, P60, STI1, STI1L, stress induced phosphoprotein 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
STIP1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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