Mouse SLAM Family Member 5 (CD84) Protein (Active)
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Description
Mouse CD84 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse CD84 isoform 1 (Q18PI6-1) extracellular domain (Met 1-Val 221) was expressed, with a polyhistidine tag at the C-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CD84 |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 24 kDa Sequence Fragment: Met1-Val221 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 97% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q18PI6-1 |
| Alias | LY9B,Hcd84,mCD84,SLAMF5,SLAM family member 5,Cell surface antigen MAX.3,Hly9-beta,Leukocyte differentiation antigen CD84,Signaling lymphocytic activation molecule 5 |
| Background | Protein CD84 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD84 is a surface glycoprotein that belongs to the Signaling Lymphocytic Activation Molecule (SLAM) family of receptors, which are part of the larger immunoglobulin superfamily (IgSF). It plays a significant role in the regulation of immune cell interactions, particularly in B and T lymphocytes, natural killer (NK) cells, and myeloid cells. CD84 is predominantly expressed in hematopoietic cells, where it mediates cell signaling processes related to immune regulation, cell adhesion, and inflammatory responses. CD84 is encoded by the CD84 gene, which is located on chromosome 1q23. It is widely expressed on immune cells such as B cells, T cells, dendritic cells, and monocytes, with notable expression also found on platelets. This molecule is critical for maintaining the balance of immune responses, including both activation and inhibition of immune functions. Due to its regulatory functions, CD84 has attracted considerable attention in immunology, cancer research, and autoimmune disease studies.
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