Mouse Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) ELISA Kit

Este producto es parte de SIT1 - Signaling threshold-regulating transmembrane adapter 1
Mouse Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for SIT1

proveedor

Abbexa

reference

abx545966

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Signaling Threshold-Regulating Transmembrane Adapter 1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1), also known as SIT, is an immunoregulatory protein primarily expressed in T cells. It acts as a transmembrane adaptor involved in modulating T-cell receptor (TCR) signaling by interacting with key intracellular signaling molecules such as Src family kinases and SH2 domain-containing phosphatases. SIT1 fine-tunes immune responses by negatively regulating TCR-mediated activation, thus maintaining immune tolerance and preventing overactivation that could lead to autoimmune diseases. Its dysregulation is associated with immune disorders and may affect T-cell maturation and peripheral immune homeostasis.

Características del producto

category

ELISA Kits


immunogen target

Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.07 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

SIT1, SIT, SIT-R, signaling threshold regulating transmembrane adaptor 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

SIT1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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