Mouse Sialomucin Core Protein 24 (CD164) Protein

Este producto es parte de CD164 - CD164 molecule
Mouse Sialomucin Core Protein 24 (CD164) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein CD164

proveedor

Abbexa

reference

abx168710

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse CD164 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

CD164, also known as endolyn or sialomucin core protein 24 (MUC24), is a transmembrane protein involved in cell adhesion and cellular signaling. Expressed predominantly on the surface of hematopoietic progenitor cells and certain epithelial cells, CD164 plays a pivotal role in the regulation of cell migration, proliferation, and differentiation, especially within the hematopoietic system. Located on chromosome 6q21 in humans, the CD164 gene encodes a member of the sialomucin family, which is characterized by its extensive glycosylation and sialic acid residues. CD164 is a crucial molecule in hematopoiesis, as it contributes to the retention of hematopoietic stem cells (HSCs) in their niches and modulates the response of these cells to cytokines and growth factors. Due to its significant roles in cell adhesion and migration, CD164 has been implicated in processes such as immune cell homing, tissue regeneration, and wound healing. Additionally, it plays a role in various diseases, including cancers, where it influences tumor cell migration and metastasis. CD164 is also a biomarker in specific cancer types and a regulator of cellular responses to inflammation.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Sialomucin Core Protein 24 (CD164)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 18.5 kDa Observed MW (SDS-PAGE): 19 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln24-Asp162 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD164


dry ice

No


availability

Shipped within 5-7 working days.


alias

Sialomucin core protein 24,DFNA66,MGC-24,MUC-24,MGC-24v,endolyn,Multi-glycosylated core protein 24


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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