Mouse Serum Amyloid P-Component (APCS) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Serum Amyloid P-Component (APCS) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Serum Amyloid P Component (SAP)No significant cross-reactivity or interference between Serum Amyloid P Component (SAP) and analogues was observed.
SAP, also known as PTX2, belongs to the pentraxin family. Has the ability to bind ligands in a calcium-dependent manner and its unique flattened β-jellyroll structure, which bears resemblance to the structure found in legume lectins. APCS is its human gene.SAP is exclusively produced in the liver, and as a standard plasma protein, it is naturally present in all individuals. While it enters the brain in only minuscule quantities under normal conditions, it is consistently found in the cerebrospinal fluid. AP possesses the capacity to bind to both amyloid plaques and tau tangles, effectively stabilizing and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal. It ia also known as: APCS, PTX2, SAP, AP, Amyloid P Component
SAP, también conocida como PTX2, pertenece a la familia de las pentraxinas. Tiene la capacidad de unirse a ligandos de una manera dependiente del calcio y su estructura única de β-jellyroll aplanada, que se parece a la estructura que se encuentra en las lectinas de las leguminosas. APCS es su gen humano. La SAP se produce exclusivamente en el hígado y, como proteína plasmática estándar, está presente de forma natural en todos los individuos. Si bien ingresa al cerebro sólo en cantidades minúsculas en condiciones normales, se encuentra constantemente en el líquido cefalorraquídeo. AP posee la capacidad de unirse tanto a placas amiloides como a ovillos de tau, estabilizando y estabilizando eficazmente los agregados al prevenir la escisión proteolítica y, por lo tanto, inhibir la eliminación de fibrillas. También se conoce como: APCS, PTX2, SAP, AP, componente amiloide P.
ELISA Kits
Serum Amyloid P-Component (APCS)
Mouse
3.12 ng/ml - 200 ng/ml
< 1.37 ng/ml
Sandwich
Quantitative
Colorimetric
Serum,Plasma,Other biological fluids
96 tests
5 × 96 tests
10 × 96 tests
APCS,PTX2,Ptx2,Sap
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
APCS
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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