Mouse Serpin B8 (SerpinB8) Protein

1235€ (100 µg)
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935106861
info@markelab.com
name
Mouse Serpin B8 (SerpinB8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691962
tested applications
SDS-PAGE
Description
Mouse SerpinB8 Protein is a recombinant protein from Mouse produced in Baculovirus-Insect Cells. A DNA sequence encoding the mouse SERPINB8 (NP_035589.1) (Met 1-Pro 374) was expressed,with a C-terminal polyhistidine tag.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | SerpinB8 |
Host | Insect |
Origin | Mouse |
Observed MW | Molecular Weight: 43.6 kDa Sequence Fragment: Met1-Pro374 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
Expression | Recombinant |
Purity | > 94% (SDS-PAGE) |
Size 1 | 100 µg |
Tested Applications | SDS-PAGE |
Buffer | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0. |
Availability | Shipped within 5-15 working days. |
Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O08800 |
NCBI Accession | NP_035589.1 |
Alias | PI8,CAP2,PI-8,PSS5,C18orf53,Serpin B8,Cytoplasmic antiproteinase 2,Peptidase inhibitor 8 |
Background | Protein SERPINB8 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SERPINB8 is part of the broader serine protease inhibitor (serpin) superfamily, which plays a crucial role in regulating protease activity within various physiological processes. This gene is located on chromosome 18q21.3 and encodes an intracellular protein that is primarily involved in inhibiting serine proteases, similar to other members of the SERPINB clade. The serpin superfamily is well-known for its diverse roles in cellular processes, including inflammation, coagulation, immune response, and apoptosis. SERPINB8, in particular, has been identified as an important player in several pathological conditions, especially those related to skin integrity and immune responses. Its expression is noted across multiple tissues, with significant roles in epithelial tissues such as the skin. The protein’s involvement in inflammatory skin diseases, along with its role in other cellular processes, makes it a critical subject of study in molecular biology and medicine.
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