Semaphorin 7A Protein is a recombinant Mouse protein expressed in E. coli.
Semaphorins constitute a large family of cell surface and secreted guidance molecules, categorized into eight classes due to their structural variations, They show a conserved sema domain in their N-terminal region. They primarily function as short-range inhibitory signals, particularly crucial in directing axons away from inappropriate areas, especially during neural system development. Plexins are the primary receptors for semaphorins, often working alongside neuropilins as co-receptors in receptor complexes. These molecules have various roles, and some classes of semaphorins (SEMA3,SEMA4,SEMA4,SEMA6 ,SEMA7)are found in vertebrates, contributing to processes like atherosclerosis by affecting endothelial function, leukocyte infiltration, monocyte-macrophage retention, platelet hyperreactivity, and neovascularization. Semaphorin 7A (SEMA7A), also referred to as CD108 (Cluster of Differentiation 108) and known for the John-Milton-Hagen (JMH) blood group antigen, is a membrane-bound semaphorin that attaches to cell surfaces through a glycosylphosphatidylinositol (GPI) linkage. SEMA7A is expressed by various lymphoid and myeloid cell types and plays a significant role as an immunomodulator.
Proteins and Peptides
Mouse
E. coli
Semaphorin 7A (SEMA7A)
E. coli
Unconjugated
Lyophilized
WB, SDS-PAGE
10 µg
50 µg
100 µg
200 µg
1 mg
Recombinant
> 95%
Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
SEMA7A
No
Shipped within 5-7 working days.
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
Precio a consultar
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