Mouse Semaphorin 7A (SEMA7A) CLIA Kit

Este producto es parte de SEMA7A - semaphorin 7A
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Mouse Semaphorin 7A (SEMA7A) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196261
tested applications
CLIA

Description

Mouse Semaphorin 7A (SEMA7A) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Semaphorin 7A (SEMA7A).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryCLIA Kits
Immunogen TargetSemaphorin 7A (SEMA7A)
ReactivityMouse
Detection MethodChemiluminescent
Assay DataQuantitative
Assay TypeSandwich
Test Range62.5 pg/ml - 4000 pg/ml
Sensitivity37.5 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsCLIA
Sample TypeSerum, plasma and other biological fluids.
AvailabilityShipped within 5-12 working days.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasJohnMiltonHagen blood group,JMH,CD108,SEMAL,CDw108,PFIC11,SEMAK1,H-Sema-L,H-SEMA-K1,JMH blood group antigen,Semaphorin-K1,Semaphorin-L
BackgroundCLIA Kits SEMA7A
StatusRUO
NoteThe validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Semaphorin 7A (SEMA7A) is a membrane-associated protein that belongs to the semaphorin family, a group of proteins widely recognized for their roles in axon guidance, immune response, and cellular signaling. Semaphorins, initially identified as axon-guidance molecules, are now understood to function across a variety of biological systems, impacting cell-cell interactions, cell migration, and immune cell regulation. SEMA7A, also referred to as CD108, is distinct from other semaphorins due to its glycophosphatidylinositol (GPI) anchorage, allowing it to localize on the cell surface and interact with various receptors. SEMA7A is broadly expressed in a range of tissues, including the nervous system, immune cells, skin, and certain cancer types. It is known to participate in axonal guidance, immune regulation, bone development, and pathological conditions, such as tumorigenesis and fibrotic diseases. One of its key functions is promoting axonal outgrowth and guiding neural connections, mediated through its interactions with integrins and other receptors. Furthermore, SEMA7A is actively involved in inflammatory and immune responses, modulating immune cell migration, adhesion, and activation. This diversity in function makes SEMA7A a molecule of interest in fields ranging from neurobiology to immunology and oncology.

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