Mouse Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) ELISA Kit

Este producto es parte de CD163 - CD163 molecule
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702€ (96 tests)

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935106861
info@markelab.com
name
Mouse Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx153797
tested applications
ELISA

Description

Mouse Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Cluster Of Differentiation (CD163)

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
31.25 pg/ml - 2000 pg/ml
Sensitivity
< 13.3 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Scavenger receptor cysteine-rich type 1 protein M130,M130,MM130,SCARI1,Hemoglobin scavenger receptor
Background
Elisa kits for CD163
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

CD163, also known as the hemoglobin scavenger receptor, is a transmembrane glycoprotein expressed primarily on the surface of monocytes and macrophages. Encoded by the CD163 gene on chromosome 12 in humans, CD163 functions as a receptor for the haptoglobin-hemoglobin (Hp-Hb) complex. It is critical in scavenging free hemoglobin (Hb) released during red blood cell breakdown, thus protecting tissues from oxidative damage and inflammation due to free hemoglobin. Additionally, CD163 is part of the cysteine-rich scavenger receptor family and plays an important role in immune modulation, inflammation resolution, and tissue remodeling. Through its function as an anti-inflammatory receptor, CD163 contributes to the regulation of immune responses, often acting as a “sensor” for inflammatory conditions. When inflammation is detected, CD163-expressing cells can trigger responses that help protect tissues, making this molecule an essential component in maintaining immune homeostasis and limiting excessive immune reactions.

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