Mouse Protein Tyrosine Phosphatase Receptor Type G (PTPRG) ELISA Kit
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Description
Mouse Receptor-type tyrosine-protein phosphatase gamma (PTPRG) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Receptor-type tyrosine-protein phosphatase gamma concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein Tyrosine Phosphatase Receptor Type G (PTPRG) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q05909 |
| Gene ID | 19270 |
| Alias | PTPG,HPTPG,RPTPG,R-PTP-GAMMA,Protein-tyrosine phosphatase gamma,Receptor-type tyrosine-protein phosphatase gamma |
| Background | Elisa kits for PTPRG |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRG is a receptor-type protein tyrosine phosphatase that plays a key role in tumor suppression, immune regulation, and nervous system development. Structurally, PTPRG contains extracellular carbonic anhydrase-like and fibronectin type III domains, a transmembrane region, and two cytoplasmic phosphatase domains. PTPRG is expressed in various tissues, particularly in the brain and immune system. It regulates cellular signaling by dephosphorylating receptor tyrosine kinases (RTKs), thereby influencing cell proliferation, adhesion, and migration. PTPRG has been identified as a tumor suppressor gene in cancers such as lung, breast, and colorectal cancers. In addition, its involvement in synaptic plasticity and neuronal repair highlights its significance in neurobiology. Loss of PTPRG expression through methylation or mutations contributes to tumorigenesis and neurological disorders.
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