Mouse Ras-related protein Rab-27A (RAB27A) ELISA Kit

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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Ras-related protein Rab-27A (RAB27A) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx541477
tested applications
ELISA

Description

Mouse Ras-related protein Rab-27A (RAB27A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ras-related protein Rab-27A concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Ras-related protein Rab-27A (RAB27A)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9ERI2
Gene ID
11891
Alias
GS2,RAM,RAB27,HsT18676,GTP-binding protein Ram,Ras-related protein Rab-27A
Background
Elisa kits for RAB27A
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RAB27A, member RAS oncogene family (RAB27A) is a key regulator of vesicular trafficking, particularly in the movement of vesicles to the plasma membrane It is involved in the transport of lysosome-related organelles and granules, which play a role in processes such as immune response, secretion, and synaptic vesicle recycling RAB27A is crucial for the proper functioning of cytotoxic T lymphocytes, as it helps in the delivery of cytotoxic granules to target cells during immune responses RAB27A also contributes to the regulation of melanosome trafficking in melanocytes, impacting pigmentation processes Additionally, it has been implicated in cellular functions related to exocytosis, where it regulates the release of various molecules from cells, including neurotransmitters and hormones Dysregulation of RAB27A is linked to diseases such as Griscelli syndrome, a condition characterized by pigmentation defects, immune dysfunction, and neurological impairments Moreover, RAB27A’s role in vesicular trafficking connects it to cancer, where alterations in its function can contribute to abnormal cellular signaling, migration, and metastasis, making it a potential therapeutic target for cancer treatments

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