Mouse Putative TRAF4-associated factor 1 (TRAF4AF1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TRAF4
proveedor
Abbexareference
abx548536Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Putative TRAF4-associated factor 1 (TRAF4AF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Putative TRAF4-associated factor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TRAF4 is a unique member of the TRAF family that regulates signaling pathways involved in cellular processes such as survival, migration, and cytoskeletal organization. Unlike other TRAF proteins, TRAF4 interacts with various receptors, including TNFR superfamily members, Toll-like receptors, and growth factor receptors, linking them to downstream signaling cascades like Akt, MAPK, and NF-κB. TRAF4 is highly expressed during embryonic development and in epithelial cells, where it plays a role in tissue morphogenesis, cell polarity, and immune responses. It also participates in reactive oxygen species (ROS) regulation and ciliary function. Dysregulation of TRAF4 has been associated with cancer progression, where it promotes epithelial-mesenchymal transition (EMT), cell migration, and invasion. Knockout studies reveal defects in neural tube closure, abnormal epithelial development, and impaired ciliary function, emphasizing its roles in developmental processes and cytoskeletal regulation.
Características del producto
category
ELISA Kits
immunogen target
Putative TRAF4-associated factor 1 (TRAF4AF1)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
TRAF-4,TRAF4, CART1, MLN62, RNF83, TNF receptor associated factor 4,RING finger protein 83
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TRAF4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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