Mouse Protein LCHN (DENND11) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Protein LCHN (DENND11) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx530794
tested applications
ELISA
Description
Mouse Protein LCHN (DENND11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Protein LCHN concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein LCHN (DENND11) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q3UHG7 |
| Alias | LCHN,PRO2561,KIAA1147,Protein LCHN |
| Background | Elisa kits for DENND11 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DENN domain containing 11 (DENND11) is another member of the DENN family, functioning as a guanine nucleotide exchange factor (GEF) for Rab GTPases, with roles in vesicular trafficking and cellular organization. DENND11 is involved in regulating autophagy and endocytosis, contributing to the formation and maturation of autophagosomes and the recycling of endocytic vesicles. The DENN domain facilitates the activation of Rab GTPases by promoting GDP-GTP exchange, thereby modulating vesicular transport and membrane fusion events. DENND11 is highly expressed in certain tissues, particularly those with high vesicle trafficking demands, such as neuronal and epithelial cells. Mutations or dysregulation of DENND11 have been associated with neurological disorders and impaired autophagic flux, highlighting its role in maintaining cellular proteostasis and function.
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