Mouse Protein FAM45A (DENND10) ELISA Kit

Este producto es parte de DENND - DENN domain containing
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Protein FAM45A (DENND10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx523217
tested applications
ELISA

Description

Mouse Protein FAM45A (DENND10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Protein FAM45A concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Protein FAM45A (DENND10)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9D8N2
Gene ID
67894
Alias
FAM45A,Protein FAM45A
Background
Elisa kits for DENND10
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

DENN domain containing 10 (DENND10) is a member of the DENN domain-containing protein family, which functions as guanine nucleotide exchange factors (GEFs) for small GTPases, particularly members of the Rab family. DENND10 is specifically involved in regulating intracellular vesicle trafficking by activating Rab proteins, facilitating membrane dynamics and cargo transport within the endosomal system. The DENN domain within DENND10 mediates interactions with GDP-bound Rab proteins, catalyzing their exchange to the active GTP-bound state. DENND10 has been implicated in processes such as endosomal recycling, cell signaling, and cellular homeostasis. Dysregulation of DENND10 has been linked to disorders involving disrupted vesicle trafficking, although its specific contributions to disease mechanisms remain an area of active research. Its broad expression pattern across tissues underscores its importance in maintaining intracellular transport and cellular function.

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