Mouse Protein argonaute-1 (AGO1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Protein argonaute-1 (AGO1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501291
tested applications
ELISA
Description
Mouse Protein argonaute-1 (AGO1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Protein argonaute-1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein argonaute-1 (AGO1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8CJG1 |
| Gene ID | 236511 |
| Alias | Q99,EIF2C,hAgo1,EIF2C1,GERP95,NEDLBAS |
| Background | Elisa kits for AGO1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGO1 is a member of the Argonaute protein family, essential for the RNA-induced silencing complex (RISC), a key player in RNA interference (RNAi) and microRNA (miRNA)-mediated gene regulation. AGO1 primarily binds to miRNAs and facilitates the repression of target mRNA translation without significant endonucleolytic cleavage. Structurally, it contains conserved domains, including the PAZ domain, which binds the 3' end of small RNAs, and the PIWI domain, which has weak or no slicer activity in AGO1. AGO1 is expressed ubiquitously, with a role in post-transcriptional regulation in various biological processes, such as cell proliferation, differentiation, and stress responses. Dysregulation of AGO1 has been linked to diseases such as cancer and autoimmune disorders, where abnormal miRNA-mediated silencing affects critical pathways.
