Mouse Platelet Glycoprotein Ib Alpha Chain (GP1Ba) Protein

234€ (10 µg)
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935106861
info@markelab.com
name
Mouse Platelet Glycoprotein Ib Alpha Chain (GP1Ba) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168432
tested applications
WB, SDS-PAGE
Description
Glycoprotein Ib Alpha Polypeptide, Platelet Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Platelet Glycoprotein Ib Alpha Chain (GP1BA) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 33.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln17-Thr282 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | BSS,GP1B,VWDP,CD42B,GPIbA,BDPLT1,BDPLT3,DBPLT3,GPIbalpha,CD42b-alpha,Platelet glycoprotein Ib alpha chain,GP-Ib alpha,GPIb-alpha, Glycoprotein Ibalpha,CD42b-alpha |
Background | Protein GP1BA |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Glycoprotein Ib platelet subunit alpha (GP1BA) is a critical component of the glycoprotein Ib-IX-V complex (GPIb-IX-V) on the surface of platelets. This complex plays a central role in the process of hemostasis, specifically in the adhesion of platelets to the damaged endothelium at sites of vascular injury. Hemostasis is crucial for preventing blood loss and initiating the wound healing process, and the proper functioning of the GPIb-IX-V complex is vital for platelet tethering under high shear stress conditions, such as in arterioles. GP1BA is the alpha subunit of GPIb, which is responsible for mediating the interaction with von Willebrand factor (vWF), a plasma glycoprotein that anchors platelets to the site of injury. Through its interactions with vWF, GP1BA enables the binding of platelets to exposed subendothelial matrix components, initiating platelet activation and aggregation.
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