Mouse Platelet Glycoprotein Ib Alpha Chain (GP1Ba) Protein

Este producto es parte de GP1BA - glycoprotein Ib platelet subunit alpha
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234€ (10 µg)

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935106861
info@markelab.com
name
Mouse Platelet Glycoprotein Ib Alpha Chain (GP1Ba) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168432
tested applications
WB, SDS-PAGE

Description

Glycoprotein Ib Alpha Polypeptide, Platelet Protein is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Platelet Glycoprotein Ib Alpha Chain (GP1BA)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 33.3 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Gln17-Thr282

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
BSS,GP1B,VWDP,CD42B,GPIbA,BDPLT1,BDPLT3,DBPLT3,GPIbalpha,CD42b-alpha,Platelet glycoprotein Ib alpha chain,GP-Ib alpha,GPIb-alpha, Glycoprotein Ibalpha,CD42b-alpha
Background
Protein GP1BA
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Glycoprotein Ib platelet subunit alpha (GP1BA) is a critical component of the glycoprotein Ib-IX-V complex (GPIb-IX-V) on the surface of platelets. This complex plays a central role in the process of hemostasis, specifically in the adhesion of platelets to the damaged endothelium at sites of vascular injury. Hemostasis is crucial for preventing blood loss and initiating the wound healing process, and the proper functioning of the GPIb-IX-V complex is vital for platelet tethering under high shear stress conditions, such as in arterioles. GP1BA is the alpha subunit of GPIb, which is responsible for mediating the interaction with von Willebrand factor (vWF), a plasma glycoprotein that anchors platelets to the site of injury. Through its interactions with vWF, GP1BA enables the binding of platelets to exposed subendothelial matrix components, initiating platelet activation and aggregation.

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