Mouse PHD finger protein 10 (PHF10) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse PHD finger protein 10 (PHF10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx538644
tested applications
ELISA
Description
Mouse PHD finger protein 10 (PHF10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PHD finger protein 10 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | PHD finger protein 10 (PHF10) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9D8M7 |
| Gene ID | 72057 |
| Alias | BAF45A,SMARCG4,XAP135,BRG1-associated factor 45a |
| Background | Elisa kits for PHF10 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PHF10 is a chromatin-remodeling protein that acts as a subunit of the BAF (SWI/SNF) complex, which regulates transcription by altering nucleosome positioning and chromatin accessibility. Through its PHD domain, PHF10 interacts with histone modifications, particularly methylated and acetylated histones, facilitating recruitment of chromatin remodeling factors to target loci. PHF10 plays a crucial role in processes such as cellular differentiation, proliferation, and DNA repair by modulating transcriptional programs in a cell-specific manner. It is highly expressed in neural and embryonic tissues, where it contributes to neural development and stem cell maintenance. Dysregulation of PHF10 is implicated in neurodevelopmental disorders, immune dysfunction, and cancers, particularly melanoma and glioblastoma, where aberrant chromatin remodeling leads to altered gene expression. Knockout studies reveal impaired cellular differentiation, reduced chromatin accessibility, and defective transcriptional regulation, underscoring its role in epigenetic control, development, and disease progression.
Related Products
Recombinant Human PHF10
Ver Producto
PHD Finger Protein 10 (PHF10) Antibody
PHF10 Antibody is a Rabbit Polyclonal against PHF10.
Ver Producto