Mouse Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1) ELISA Kit

Este producto es parte de CARD - Caspase recruitment domain-containing protein
Mouse Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1) ELISA Kit
715€ (96 tests)

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Name
Mouse Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx555520
Tested Applications
ELISA

Description

Mouse Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Nucleotide-binding oligomerization domain-containing protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Nucleotide-Binding Oligomerization Domain-Containing Protein 1 (NOD1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.312 ng/ml - 20 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 1-3 weeks.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8BHB0
Alias
CARD4, CLR7.1, NLRC1, nucleotide binding oligomerization domain containing 1
Background
Elisa Kits for: NOD1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

NOD1 (Nucleotide-binding Oligomerization Domain Containing 1) is an intracellular protein involved in the immune response, particularly in the recognition of bacterial pathogens. It is a member of the NOD-like receptor (NLR) family and plays a crucial role in activating innate immunity. NOD1 detects specific bacterial peptidoglycan fragments, triggering a signaling cascade that leads to the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and other inflammatory pathways. This process results in the production of pro-inflammatory cytokines that help recruit immune cells to the site of infection. NOD1's role in inflammation also links it to various diseases, including inflammatory bowel disease (IBD), atherosclerosis, and other conditions where immune system dysregulation is evident. NOD1 has also been implicated in cancer biology due to its influence on tumor-promoting inflammatory responses.

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