Mouse Nucleoporin 214 kDa (NUP214) ELISA Kit

715€ (96 tests)
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name
Mouse Nucleoporin 214 kDa (NUP214) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx352914
tested applications
ELISA
Description
Mouse Nucleoporin 214 kDa (NUP214) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Nucleoporin 214 kDa (NUP214) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | Nucleoporin 214 kDa (NUP214) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.312 ng/ml - 20 ng/ml |
Sensitivity | 0.19 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q80U93 |
Gene ID | 227720 |
NCBI Accession | NP_758472.2 |
Alias | CAN,CAIN,IIAE9,nuclear pore complex protein Nup214,CAN protein, putative oncogene,nucleoporin 214kDa |
Background | Elisa kits for NUP214 |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nucleoporin 214 (NUP214) is a critical component of the nuclear pore complex, contributing to the regulation of nucleocytoplasmic transport NUP214 is involved in the formation of the pore’s central channel, which facilitates the selective exchange of molecules, such as RNA, ribosomal subunits, and proteins, between the nucleus and the cytoplasm It plays a key role in the movement of various signaling proteins and RNA species that regulate cellular processes like gene expression, DNA repair, and cellular stress responses NUP214 also helps ensure the integrity of the nuclear envelope during cell division and is essential for maintaining nuclear function through proper nucleocytoplasmic exchange Dysregulation of NUP214 has been linked to various cancers, where altered nuclear transport contributes to tumorigenesis and metastasis Additionally, NUP214 is associated with certain viral infections, as it can impact the movement of viral components between the nucleus and cytoplasm, influencing the viral replication cycle
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