Mouse Nucleoporin 214 kDa (NUP214) ELISA Kit

Este producto es parte de NUP - nucleoporin
Mouse Nucleoporin 214 kDa (NUP214) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

611€ (96 tests)

Elisa kits for NUP214

proveedor

Abbexa

reference

abx352914

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Nucleoporin 214 kDa (NUP214) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Nucleoporin 214 kDa (NUP214) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Nucleoporin 214 (NUP214) is a critical component of the nuclear pore complex, contributing to the regulation of nucleocytoplasmic transport NUP214 is involved in the formation of the pore’s central channel, which facilitates the selective exchange of molecules, such as RNA, ribosomal subunits, and proteins, between the nucleus and the cytoplasm It plays a key role in the movement of various signaling proteins and RNA species that regulate cellular processes like gene expression, DNA repair, and cellular stress responses NUP214 also helps ensure the integrity of the nuclear envelope during cell division and is essential for maintaining nuclear function through proper nucleocytoplasmic exchange Dysregulation of NUP214 has been linked to various cancers, where altered nuclear transport contributes to tumorigenesis and metastasis Additionally, NUP214 is associated with certain viral infections, as it can impact the movement of viral components between the nucleus and cytoplasm, influencing the viral replication cycle

Características del producto

category

ELISA Kits


immunogen target

Nucleoporin 214 kDa (NUP214)


reactivity

Mouse


test range

0.312 ng/ml - 20 ng/ml


sensitivity

0.19 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

CAN,CAIN,IIAE9,nuclear pore complex protein Nup214,CAN protein, putative oncogene,nucleoporin 214kDa


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NUP214


dry ice

No


NCBI accession

NP_758472.2


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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