Mouse Nuclear receptor subfamily 1 group D member 1 (NR1D1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Nuclear receptor subfamily 1 group D member 1 (NR1D1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx535803
tested applications
ELISA
Description
Mouse Nuclear receptor subfamily 1 group D member 1 (NR1D1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Nuclear receptor subfamily 1 group D member 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nuclear receptor subfamily 1 group D member 1 (NR1D1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q3UV55 |
| Gene ID | 217166 |
| Alias | EAR1,hRev,THRA1,THRAL,ear-1,REVERBA,REVERBalpha,V-erbA-related protein 1 |
| Background | Elisa kits for NR1D1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nuclear receptor subfamily 1 group D member 1 (NR1D1), also known as Rev-Erbα, is a nuclear receptor that plays a key role in regulating the circadian rhythm, metabolism, and inflammation NR1D1 functions by binding to DNA and regulating the expression of genes involved in lipid metabolism, glucose homeostasis, and inflammatory responses It works in opposition to other nuclear receptors, such as RORs (retinoic acid receptor-related orphan receptors), to control circadian clock genes and maintain the balance between the sleep-wake cycle and metabolic processes NR1D1 also has a role in regulating the immune system, where it modulates the expression of genes involved in immune responses and inflammatory pathways Dysregulation of NR1D1 expression or activity has been linked to metabolic disorders, such as obesity, diabetes, and cardiovascular diseases, as well as immune-related conditions like atherosclerosis and rheumatoid arthritis Its involvement in the regulation of daily metabolic rhythms also makes NR1D1 a potential target for therapies aimed at treating sleep disorders, metabolic diseases, and chronic inflammatory conditions
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