Mouse N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits GCNT2
proveedor
Abbexareference
abx525005Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Glucosaminyl (N-acetyl) transferase 2 (GCNT2), also known as the I-branching enzyme, catalyzes the addition of N-acetylglucosamine to linear oligosaccharides, forming the branched I antigen structure that characterizes the I blood group system GCNT2 is predominantly expressed in erythroid cells, epithelial tissues, and during embryonic development, where it is critical for glycan diversity and proper glycoprotein function Mutations in GCNT2 lead to the adult i phenotype, a rare blood group disorder characterized by persistent fetal-type linear glycans, hemolytic anemia, and immune vulnerabilities GCNT2’s activity also influences ocular health, with mutations linked to congenital cataracts and other lens abnormalities Emerging research highlights its role in embryogenesis and cell surface glycosylation, critical for cell signaling, adhesion, and differentiation Dysregulation of GCNT2 expression has further been associated with immune dysfunction and specific cancer pathways, emphasizing its role in glycoprotein branching and cellular homeostasis
Características del producto
category
ELISA Kits
immunogen target
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
N-acetylglucosaminyltransferase,I-branching enzyme,CCAT,CTRCT13,GCNT2C,GCNT5,IGNT,NACGT1,NAGCT1,ULG3,bA360O19.2,bA421M1.1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
GCNT2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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