Mouse N-Acetylgalactosaminidase Alpha (NAGA) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein NAGA
proveedor
Abbexareference
abx068200Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant N-Acetylgalactosaminidase Alpha (NAGa) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
N-Acetylgalactosaminidase Alpha (NAGA) is an enzyme involved in the breakdown of complex carbohydrates. catalyzes the hydrolysis of terminal alpha-N-acetylgalactosaminyl residues in glycoproteins and glycolipids (lysosomes), Deficiency in NAGA enzyme activity leads to a rare genetic disorder known as Schindler disease, which is characterized by the accumulation of certain glycoproteins and glycolipids in lysosomes. Schindler disease can manifest in different forms, including Schindler disease type I and type II, depending on the severity of the enzyme deficiency. Symptoms of Schindler disease can vary widely but may include developmental delay, intellectual disability, seizures, skeletal abnormalities, and other neurological and systemic manifestations. The severity and progression of the disease can also vary, ranging from mild to severe.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
N-Acetylgalactosaminidase Alpha (NAGA)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 24.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile218-Trp415 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NAGA
dry ice
No
availability
Shipped within 5-12 working days.
alias
GALB, D22S674
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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