Mouse Myosin Binding Protein C, Slow Type (MYBPC1) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Mouse Myosin Binding Protein C, Slow Type (MYBPC1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx165934
tested applications
WB, SDS-PAGE
Description
Myosin Binding Protein C, Slow Type is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Myosin Binding Protein C, Slow Type (MYBPC1) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Leu277 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | LCCS4,CMYP16,MYBPCC,MYBPCS,MYOTREM,ssMyBP-C,Slow MyBP-C,C-protein skeletal muscle slow isoform |
| Background | Protein MYBPC1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
MYBPC1 is a structural protein predominantly expressed in slow-twitch skeletal muscles, where it plays a critical role in maintaining the structural integrity of sarcomeres and regulating muscle contraction. By interacting with myosin and actin filaments, it modulates their binding interactions and stabilizes the thick filaments within the muscle fibers. This ensures the proper alignment and function of the contractile apparatus. Mutations in MYBPC1 have been associated with various myopathies, including those characterized by muscle weakness and reduced contractility, particularly in conditions affecting slow-twitch muscles. These mutations can lead to disruptions in sarcomere assembly and force transmission. MYBPC1’s role in muscle biomechanics makes it an important focus of research into muscle function and disease mechanisms.
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