Mouse Mitogen-activated protein kinase kinase kinase 3 (MAP3K3) ELISA Kit
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Description
Mouse Mitogen-activated protein kinase kinase kinase 3 (MAP3K3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Mitogen-activated protein kinase kinase kinase 3 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
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Product specifications
| Category | ELISA Kits |
| Immunogen Target | Mitogen-activated protein kinase kinase kinase 3 (MAP3K3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q61084 |
| Gene ID | 26406 |
| Background | Elisa kits for MAP3K3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
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The mitogen-activated protein/ERK kinase kinase 3(MEKK3) is a member of a family of MEKK/Ste11 serine/threonine protein kinases. One function of MEKK3 is to serve as an upstream regulatory kinase in the mitogen-activated protein kinase cascade, however, it also plays a critical role in other signaling pathways. MEKK3 regulates several important functions including cell survival and proliferation. It is ubiquitously expressed in multiple tissues and has been found in complexes with scaffold proteins and other kinases.(PMID: 18206350).Cerebral cavernous malformations(CCMs) complex regulation of MEKK3 is essential during vertebrate heart development. MEKK3 signalling and KLF2/4 may be targeted to develop new CCM therapeutics.
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