Mouse Lysosome-associated membrane glycoprotein 3 (LAMP3) ELISA Kit

Este producto es parte de LAMP- Lysosomal Associated Membrane Protein
Mouse Lysosome-associated membrane glycoprotein 3 (LAMP3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LAMP3

proveedor

Abbexa

reference

abx530670

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Lysosome-associated membrane glycoprotein 3 (LAMP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lysosome-associated membrane glycoprotein 3 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Lysosome-associated membrane glycoprotein 3 (LAMP3), also known as DC-LAMP, is a lysosomal membrane protein predominantly expressed in dendritic cells and other immune cells, where it plays a critical role in antigen processing and presentation LAMP3 expression increases during dendritic cell maturation, facilitating the regulation of lysosomal function and endosomal trafficking It is also involved in lysosome-mediated autophagy and immune responses by regulating cellular degradation pathways Dysregulation of LAMP3 has been linked to cancer progression and metastasis, particularly in breast, cervical, and lung cancers, where its overexpression promotes tumor cell survival and invasion through altered lysosomal activity Additionally, LAMP3 has been implicated in hypoxia response pathways, contributing to cellular adaptation to low oxygen environments Emerging studies highlight its role in viral infections, where it can affect viral replication and host immune response, making LAMP3 a potential biomarker for immune regulation and cancer prognosis

Características del producto

category

ELISA Kits


immunogen target

Lysosome-associated membrane glycoprotein 3 (LAMP3)


reactivity

Mouse


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 36 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CD208,DC LAMP,DC-LAMP,DCLAMP,LAMP,LAMP-3,TSC403,DC-lysosome-associated membrane glycoprotein


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LAMP3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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