Mouse Lysosomal Associated Membrane Protein 2 (LAMP2) ELISA Kit

Este producto es parte de LAMP- Lysosomal Associated Membrane Protein
Mouse Lysosomal Associated Membrane Protein 2 (LAMP2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LAMP2

proveedor

Abbexa

reference

abx517054

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Lysosomal Associated Membrane Protein 2 (LAMP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lysosomal Associated Membrane Protein 2 (LAMP2) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Lysosome-associated membrane glycoprotein 2 (LAMP2) is a critical lysosomal membrane protein involved in autophagy, lysosomal biogenesis, and cellular homeostasis LAMP2 facilitates the fusion of autophagosomes with lysosomes, enabling the degradation of cellular components during autophagy LAMP2 exists in three isoforms (LAMP2A, LAMP2B, and LAMP2C), each with distinct roles in lysosome function LAMP2A is essential for chaperone-mediated autophagy (CMA), where it mediates the selective degradation of cytosolic proteins LAMP2B is primarily involved in macroautophagy, particularly in muscle and neuronal tissues Mutations in LAMP2 cause Danon disease, a rare lysosomal storage disorder characterized by cardiomyopathy, myopathy, and intellectual disability LAMP2 dysregulation has been linked to neurodegenerative diseases and cancers, where impaired autophagy disrupts cellular homeostasis and promotes disease progression LAMP2 also plays a role in immune responses, contributing to antigen processing and lysosomal exocytosis Its importance in autophagy, cellular stress responses, and disease underscores its critical role in maintaining cellular integrity

Características del producto

category

ELISA Kits


immunogen target

Lysosomal Associated Membrane Protein 2 (LAMP2)


reactivity

Mouse


test range

0.312 ng/ml - 20 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CD107b,DND,LAMP-2,LAMPB,LGP-96,LGP110


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LAMP2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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