Mouse Lutropin-Choriogonadotropic Hormone Receptor (LHCGR) ELISA Kit

Este producto es parte de LHCGR - Luteinizing Hormone Receptor
Mouse Lutropin-Choriogonadotropic Hormone Receptor (LHCGR) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

559€ (96 tests)

Elisa kits for LHCGR

proveedor

Abbexa

reference

abx254956

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Lutropin-Choriogonadotropic Hormone Receptor (LHCGR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lutropin-choriogonadotropic hormone receptor concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

LHCGR is a G protein-coupled receptor activated by luteinizing hormone (LH) and human chorionic gonadotropin (hCG), playing a crucial role in reproductive function. It is expressed in ovarian theca and granulosa cells in females and Leydig cells in males. In females, LHCGR regulates ovulation, corpus luteum formation, and progesterone production during the menstrual cycle and pregnancy. In males, LHCGR stimulates testosterone synthesis in Leydig cells, which supports spermatogenesis. LHCGR signaling activates adenylyl cyclase through Gs proteins, increasing cAMP levels and activating protein kinase A (PKA), which regulates steroidogenesis and cell proliferation. Mutations in LHCGR are linked to disorders such as precocious puberty, infertility, and hypogonadism. Overexpression of LHCGR has been observed in hormone-dependent cancers, including ovarian and testicular tumors, where it drives abnormal growth and survival. Therapeutically, LH/hCG analogs are used to treat infertility, while LHCGR antagonists are being explored for hormone-related cancers. LHCGR is vital for maintaining reproductive health and steroid hormone production.

Características del producto

category

ELISA Kits


immunogen target

Lutropin-Choriogonadotropic Hormone Receptor (LHCGR)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

LHCGR,Choriogonadotropin receptor,LCGR,LGR2,LHR, lutropin-choriogonadotropic hormone receptor,LH-R,Luteinizing Hormone/Choriogonadotropin Receptor, HHG,LH/CG-R,LH/CGR,LHR,LHRHR,LSH-R,ULG5


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LHCGR


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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