Mouse Lutropin-Choriogonadotropic Hormone Receptor (LHCGR) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
559€ (96 tests)
Elisa kits for LHCGR
proveedor
Abbexareference
abx254956Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Lutropin-Choriogonadotropic Hormone Receptor (LHCGR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lutropin-choriogonadotropic hormone receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LHCGR is a G protein-coupled receptor activated by luteinizing hormone (LH) and human chorionic gonadotropin (hCG), playing a crucial role in reproductive function. It is expressed in ovarian theca and granulosa cells in females and Leydig cells in males. In females, LHCGR regulates ovulation, corpus luteum formation, and progesterone production during the menstrual cycle and pregnancy. In males, LHCGR stimulates testosterone synthesis in Leydig cells, which supports spermatogenesis. LHCGR signaling activates adenylyl cyclase through Gs proteins, increasing cAMP levels and activating protein kinase A (PKA), which regulates steroidogenesis and cell proliferation. Mutations in LHCGR are linked to disorders such as precocious puberty, infertility, and hypogonadism. Overexpression of LHCGR has been observed in hormone-dependent cancers, including ovarian and testicular tumors, where it drives abnormal growth and survival. Therapeutically, LH/hCG analogs are used to treat infertility, while LHCGR antagonists are being explored for hormone-related cancers. LHCGR is vital for maintaining reproductive health and steroid hormone production.
Características del producto
category
ELISA Kits
immunogen target
Lutropin-Choriogonadotropic Hormone Receptor (LHCGR)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
LHCGR,Choriogonadotropin receptor,LCGR,LGR2,LHR, lutropin-choriogonadotropic hormone receptor,LH-R,Luteinizing Hormone/Choriogonadotropin Receptor, HHG,LH/CG-R,LH/CGR,LHR,LHRHR,LSH-R,ULG5
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
LHCGR
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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