Mouse Lipopolysaccharide Binding Protein (LBP) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein LBP
proveedor
Abbexareference
abx067809Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse Lipopolysaccharide Binding Protein (LBP) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
LBP is an acute-phase protein produced mainly by the liver in response to infections and inflammation It plays a crucial role in innate immunity by binding to lipopolysaccharides (LPS) from the outer membrane of Gram-negative bacteria and delivering them to CD14 and Toll-like receptor 4 (TLR4) complexes on immune cells This process triggers signaling pathways that lead to the production of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6, initiating immune defense against bacterial infections Elevated LBP levels are observed in sepsis, systemic inflammatory response syndrome (SIRS), and chronic inflammatory diseases Dysregulation of LBP contributes to endotoxemia, where excessive immune activation results in tissue damage and organ failure It is a valuable biomarker for assessing infection severity and therapeutic outcomes in sepsis and inflammatory conditions
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Lipopolysaccharide Binding Protein (LBP)
host
E. coli
conjugation
Unconjugated
form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 27.5 kDa Observed MW (SDS-PAGE): 27 kDa Concentration: Prior to lyophilization: 50 µg/ml Sequence Fragment: Leu226-Pro438 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
LBP
dry ice
No
availability
Shipped within 5-7 working days.
alias
BPIFD2,BPI Fold Containing Family D,LPS-Binding Protein 3
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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